Jaguars vs. Saints odds, line, picks: 2021 NFL preseason predictions, best bets from expert on 23-12 run


After a very busy weekend of NFL preseason action, a standalone game emerges on Monday evening. The New Orleans Saints will host the Jacksonville Jaguars in front of a national audience, with both teams aiming to come back from opening defeats. The Saints, while resting numerous starters, fell to the preseason juggernaut Baltimore Ravens by a 17-14 final score last week. Jacksonville struggled offensively, particularly in the first half, on the way to a 23-13 defeat at the hands of the Cleveland Browns. Both teams have quarterback battles to monitor, with Taysom Hill vs. Jameis Winston for New Orleans and Trevor Lawrence vs. Gardner Minshew for Jacksonville.

Kickoff is at 8 p.m. ET in New Orleans. Caesars Sportsbook lists the Saints as four-point favorites at home, while the over-under, or total number of points Vegas thinks will be scored, is 39.5 in the latest Jaguars vs. Saints odds. Before you make any Saints vs. Jaguars picks, make sure to check out the expert NFL predictions from SportsLine NFL expert Mike Tierney

A national sportswriter whose work appears in The New York Times and Los Angeles Times, Tierney has covered the NFL for decades and reported from seven Super Bowls. Tierney does not consider himself a pet lover. But he likes ‘dogs, preferring to evaluate each game from the underdog’s point of view. Tierney has used that philosophy to crush the NFL, going 187-147 against the spread the past three seasons.

In addition, Tierney has gone an astounding 23-12 on his last 35 picks involving Jacksonville, returning more than $1,000. Anyone who has followed him is way up.

Now, Tierney has set his sights on Jaguars vs. Saints and just revealed his NFL expert picks and predictions. You can head to SportsLine now to see his picks. Now, here are several NFL odds and betting trends for Saints vs. Jaguars:

Jaguars vs. Saints odds, spread, over-under, money line

Jaguars vs. Saints spread: Saints -4Jaguars vs. Saints over-under: 39.5 pointsJaguars vs. Saints money line: Saints -210, Jaguars +180JAC: The Jaguars were 7-9 against the spread last seasonNO: The Saints were 10-8 against the spread in 2020

Featured Game | New Orleans Saints vs. Jacksonville Jaguars

Why the Jaguars can cover

The Jaguars have strengths to lean on in this matchup, but they could also benefit from where the Saints are at the moment. New Orleans has little depth at wide receiver, with Tre’Quan Smith recently missing two weeks of practice and All-Pro wideout Michael Thomas still out due to ankle surgery. The Saints were also incredibly sloppy in their first game, committing 10 penalties and turning the ball over six times.

The Jaguars could also benefit from the active competition at quarterback, particularly with the buzz that Lawrence is expected to start. He was effective, completing 6-of-9 passes for 71 yards, in the opener, and Lawrence building on that success could be beneficial for Jacksonville’s future. The Jags also have a much deeper stable of wide receivers, keyed by Marvin Jones, and have the benefit of intriguing players like Tavon Austin and Laquon Treadwell battling for roster spots and playing time.

Why the Saints can cover

The Saints have the superior roster and the more established culture. The Jaguars generated only 85 yards of offense in the first half of their first contest. Considering that came with Jacksonville’s first and second string on the field, the Saints can feel confident with their potent defense. 

The Jags were a bottom-three team in the NFL in both scoring defense (28.9 points allowed) and scoring offense (19.1 points per game) last season, and the Saints project to use more of their key pieces in this game. In addition, New Orleans may have a diamond in the rough in Tony Jones Jr. at the running back position. The Saints already have quality depth with superstar Alvin Kamara, Latavius Murray and Devonta Freeman, but Jones Jr. was legitimately good last week, which could help in the second half of this game. 

How to make Saints vs. Jaguars picks

Tierney is leaning over on the point total, and he’s also discovered a critical X-factor that has him jumping all over one side of the spread. He’s only sharing that pick at SportsLine

So who wins Jaguars vs. Saints? And what critical X-factor makes one side of the spread a must-back? Visit SportsLine now to see Mike Tierney’s Saints vs. Jaguars pick and analysis, all from the NFL expert who’s 23-12 on picks involving Jacksonville, and find out. 

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