NFL odds, lines, picks, spreads, best bets, predictions for Week 4, 2021: Model high on Seahawks, Browns

Carson Wentz and the Indianapolis Colts are still searching for their first win of the season. They’ll try to get off the mark against Jacoby Brissett and the Miami Dolphins on Sunday afternoon. According to the latest Week 4 NFL odds from Caesars Sportsbook, Indianapolis is a two-point underdog on the road. The Colts have dominated the Dolphins over the years, winning six of their last eight meetings against Miami. However, the Dolphins are 6-1 against the spread in their last seven games at home, making this one of the most intriguing Week 4 NFL spreads. All of the NFL lines are listed below, and before making any Week 4 NFL picks on these games or others, be sure to see the Week 4 NFL predictions from the proven computer model at SportsLine

The model, which simulates every NFL game 10,000 times, is up almost $7,900 for $100 players on top-rated NFL picks since its inception six-plus years ago. It went a sizzling 24-14 on top-rated NFL picks last season, returning more than $800. The model also enters Week 4 of the 2021 season on an incredible 123-81 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, it has turned its attention to the latest Week 4 NFL odds from Caesars and locked in picks for every NFL matchup. Head here to see every pick.

Top Week 4 NFL predictions

One of the top Week 4 NFL predictions the model recommends: The Seahawks (+3) cover the spread against the 49ers. The Seahawks have lost twice in a row after opening the season with a win, but the model likes them to get a win against the 49ers, who are coming off a last-minute loss to the Packers.

Seattle’s consecutive losses were defined by second-half slumps, as the team has only scored six points combined in the second half during the past two weeks. However, it’s not as if Russell Wilson has suddenly lost it. He still has Tyler Lockett and D.K. Metcalf at his disposal, and they could wreak havoc against an already-depleted 49ers secondary.

The model likes Seattle to win the game outright. In simulations from SportsLine’s model, Seattle wins almost 60 percent of the time. The point total goes under in almost 60 percent of simulations as well.

Another one of the top Week 4 NFL picks from the model: The Browns (-2) cover the spread on the road against the Vikings well over 50 percent of the time. Cleveland features one of the league’s stingiest defenses, giving up just 248.7 yards per game on average, which ranks third in the NFL. Last week against the Bears, the Browns recorded nine sacks.

Defensive end Myles Garrett set the single-game franchise record for sacks with 4.5 against Chicago. The Browns have 12 total sacks on the season and will now look to disrupt a Minnesota offense that is averaging 425 yards per game, which ranks third in the league.

The model has taken into account that Cleveland is 4-1 against the spread in its last five games on the road. SportsLine’s model shows Cleveland’s defense holding the Vikings well below their season average of 29 points, resulting in the Browns covering the spread in well over 50 percent of simulations.  

How to make Week 4 NFL picks 

The model has also made the call on who wins and covers in every other game on the Week 4 NFL schedule, and it’s calling for an undefeated team to go down hard. You can only get every pick for every game at SportsLine.

So what NFL picks can you make with confidence? And which undefeated team goes down hard? Check out the latest NFL odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned almost $7,900 since its inception, and find out.

Week 4 NFL odds, spreads, lines

Sunday, Oct. 3

Washington at Falcons (+1.5, 47.5)

Featured Game | Atlanta Falcons vs. Washington Football Team

Lions at Bears (-3, 41.5)

Featured Game | Chicago Bears vs. Detroit Lions

Titans at Jets (+6, 44.5)

Featured Game | New York Jets vs. Tennessee Titans

Browns at Vikings (+2, 51.5)

Featured Game | Minnesota Vikings vs. Cleveland Browns

Colts at Dolphins (-2, 42.5)

Featured Game | Miami Dolphins vs. Indianapolis Colts

Panthers at Cowboys (-4.5, 51.5)

Featured Game | Dallas Cowboys vs. Carolina Panthers

Giants at Saints (-7, 42)

Featured Game | New Orleans Saints vs. New York Giants

Chiefs at Eagles (+7, 54.5)

Featured Game | Philadelphia Eagles vs. Kansas City Chiefs

Texans at Bills (-17, 47)

Featured Game | Buffalo Bills vs. Houston Texans

Cardinals at Rams (-4, 54.5)

Featured Game | Los Angeles Rams vs. Arizona Cardinals

Seahawks at 49ers (-3, 52)

Featured Game | San Francisco 49ers vs. Seattle Seahawks

Ravens at Broncos (PK, 45)

Featured Game | Denver Broncos vs. Baltimore Ravens

Steelers at Packers (-6.5, 45.5)

Featured Game | Green Bay Packers vs. Pittsburgh Steelers

Buccaneers at Patriots (+7, 49.5)

Featured Game | New England Patriots vs. Tampa Bay Buccaneers

Monday, Oct. 4

Raiders at Chargers (-3, 51.5)

Featured Game | Los Angeles Chargers vs. Las Vegas Raiders

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