Broncos vs. Browns odds, line, spread: Thursday Night Football picks, predictions from NFL model on 125-85 run

The Cleveland Browns (3-3) and Denver Broncos (3-3) are both on losing streaks heading into their Week 7 matchup on Thursday Night Football. The Browns were defeated by the Los Angeles Chargers and Arizona Cardinals in consecutive weeks, while the Broncos started the season off 3-0 before dropping three straight. This primetime showdown is crucial for each team as they attempt to salvage their respective seasons. The Browns will be without quarterback Baker Mayfield (shoulder) and running backs Nick Chubb (calf) and Kareem Hunt (calf).

Kickoff from FirstEnergy Stadium is set for 8:20 p.m. ET. Cleveland is favored by two points in the latest Broncos vs. Browns odds from Caesars Sportsbook, while the Over-Under is 41. Before locking in any Browns vs. Broncos picks, you need to check out the NFL predictions and analysis from the proven SportsLine Projection Model

The model, which simulates every NFL game 10,000 times, is up almost $7,700 for $100 players on top-rated NFL picks since its inception six-plus years ago. It went a sizzling 24-14 on top-rated NFL picks last season, returning more than $800. The model also enters Week 7 of the 2021 season on an incredible 125-85 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has simulated Browns vs. Broncos 10,000 times and just revealed its coveted NFL picks and predictions. You can head to SportsLine now to see the model’s picks. Now, here are several NFL odds and betting lines for Browns vs. Broncos:

Broncos vs. Browns spread: Browns -2Broncos vs. Browns over-under: 41 points Broncos vs. Browns money line: Cleveland -125, Denver +105CLE: Browns are 7-3 ATS in their last 10 Thursday games  DEN: Over is 4-1 in Broncos’ last five games following a straight-up loss  

Featured Game | Cleveland Browns vs. Denver Broncos

Why the Browns can cover

The Browns have been hit hard by the injury bug in 2021. Odell Beckham Jr., Nick Chubb, Jack Conklin, A.J. Green, Kareem Hunt, Baker Mayfield, Jeremiah Owusu-Koramoah, Malcolm Smith, JC Tretter, and Jedrick Wills all missed practice Monday, and several other key players were listed on the team’s injury report.

With Mayfield unable to go, the Browns will turn to veteran backup Case Keenum, who was Denver’s starting quarterback in 2018. D’Ernest Johnson is expected to get the start at running back for Cleveland.

Defensively, the Browns are in better shape, but still have several players battling nagging injuries. With Denver’s offensive line struggling, Garrett and fellow defensive end Jadeveon Clowney could have a field day. 

Why the Broncos can cover

The Broncos currently rank fourth in total defense, allowing 314.7 total yards per game, and third in points allowed per game at 18.3. They have been particularly effective against the run in 2021, allowing only 85.5 rushing yards per game. With Baker Mayfield, Kareem Hunt, and Nick Chubb out, Denver’s defense should thrive in this matchup.

During the first three weeks of the season, the Broncos gave up a total of 26 points. They have struggled against better competition since, but with the Browns hobbling into this matchup, Denver has a significant advantage based on player availability. 

How to make Broncos vs. Browns picks 

SportsLine’s model is leaning over on the point total, projecting the teams to combine for 44 points. The model also says one side of the spread hits well over 50 percent of the time. You can only see the model’s Broncos vs. Browns picks at SportsLine.

So who wins Browns vs. Broncos on Thursday Night Football? And which side of the spread hits in well over 50 percent of simulations? Visit SportsLine now to see which side of the Browns vs. Broncos spread to jump on, all from the advanced model that is up almost $7,700 on its NFL picks, and find out.

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